Joseli Lannes-Vieira Selected Research

Heart Injuries

1/2020	CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy.
3/2015	Pentoxifylline reverses chronic experimental Chagasic cardiomyopathy in association with repositioning of abnormal CD8+ T-cell response.
1/2015	A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy.
1/2012	CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy.
1/2012	Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury.

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Joseli Lannes-Vieira Research Topics

Disease

28	Infections 01/2022 - 06/2004
18	Chagas Disease (American Trypanosomiasis) 01/2022 - 02/2003
14	Cardiomyopathies (Cardiomyopathy) 01/2022 - 06/2008
13	Heart Diseases (Heart Disease) 01/2022 - 01/2014
8	Inflammation (Inflammations) 01/2022 - 04/2003
8	Myocarditis (Carditis) 10/2016 - 04/2003
5	Persistent Infection 01/2022 - 02/2010
5	Heart Injuries 01/2020 - 01/2012
4	Fibrosis (Cirrhosis) 01/2022 - 12/2010
4	Parasitemia 01/2015 - 05/2007
3	Toxoplasmosis 01/2022 - 03/2003
3	Meningoencephalitis 10/2012 - 09/2003
2	Memory Disorders (Memory Loss) 01/2022 - 01/2021
2	Neuroinflammatory Diseases 01/2022 - 01/2021
2	Cysts 01/2022 - 01/2021
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 12/2017
2	Virus Diseases (Viral Diseases) 01/2021 - 01/2019
2	Sinus Arrhythmia 01/2019 - 10/2016
2	Necrosis 05/2018 - 06/2014
2	Shock 05/2007 - 02/2003
1	Chagas Cardiomyopathy 01/2021
1	Bradycardia 01/2020
1	Weight Loss (Weight Reduction) 12/2015
1	Hypertrophy 03/2015
1	Disease Progression 01/2015
1	Autonomic Nervous System Diseases (Dysautonomia) 11/2014
1	Cardiac Arrhythmias (Arrythmia) 11/2014
1	Atrioventricular Block 01/2014
1	Tuberculosis (Tuberculoses) 08/2013

Drug/Important Bio-Agent (IBA)

9	CytokinesIBA 01/2022 - 02/2003
8	benzonidazole (benznidazole)IBA 01/2022 - 06/2008
6	Interferon-gamma (Interferon, gamma)IBA 05/2018 - 04/2003
5	Chemokine ReceptorsIBA 04/2021 - 04/2003
5	VaccinesIBA 01/2021 - 02/2010
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2016 - 06/2008
4	Pharmaceutical PreparationsIBA 01/2022 - 03/2010
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2014
3	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2015
3	Pentoxifylline (Trental)FDA LinkGeneric 01/2022 - 03/2015
3	Met- RANTESIBA 01/2020 - 09/2004
3	CC ChemokinesIBA 01/2020 - 09/2004
3	Messenger RNA (mRNA)IBA 01/2020 - 03/2007
3	Connexin 43 (Connexin43)IBA 01/2019 - 01/2012
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2016 - 01/2012
3	PerforinIBA 01/2012 - 10/2009
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2010
2	Type I Tumor Necrosis Factor ReceptorsIBA 09/2017 - 06/2008
2	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 01/2017 - 10/2003
2	Integrin alpha4beta1 (VLA-4)IBA 01/2017 - 10/2003
2	Fibronectins (Fibronectin)IBA 03/2015 - 01/2014
2	AntibodiesIBA 11/2014 - 09/2003
2	IsoenzymesIBA 01/2012 - 01/2012
2	Thomsen-Friedenreich antibodiesIBA 01/2012 - 09/2004
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2012 - 02/2010
2	InterferonsIBA 10/2011 - 02/2010
2	InterleukinsIBA 02/2010 - 02/2003
2	Membrane Proteins (Integral Membrane Proteins)IBA 10/2009 - 09/2009
2	Cell Adhesion MoleculesIBA 07/2009 - 10/2003
2	Chemokine CCL5IBA 03/2007 - 09/2004
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 07/2004 - 10/2003
1	Biological ProductsIBA 01/2022
1	Sulfadiazine (Sulphadiazine)FDA Link 01/2022
1	methylxanthineIBA 01/2022
1	Pyrimethamine (Daraprim)FDA Link 01/2022
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2022
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	Interleukin-2 (IL2)IBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Chemotactic FactorsIBA 01/2021
1	CCR1 ReceptorsIBA 01/2020
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2020
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2020
1	Therapeutic UsesIBA 01/2019
1	ChemokinesIBA 01/2019
1	LigandsIBA 01/2019
1	4- (4- (3- (pyridin- 2- yl)- 1H- pyrazol- 4- yl)pyridin- 2- yl)- N- (tetrahydro- 2H- pyran- 4- yl)benzamideIBA 01/2019
1	Transforming Growth Factors (Transforming Growth Factor)IBA 05/2018
1	NF-kappa B (NF-kB)IBA 12/2017
1	Interleukin-6 (Interleukin 6)IBA 09/2017
1	IntegrinsIBA 01/2017
1	AntioxidantsIBA 10/2016
1	Metformin (Glucophage)FDA LinkGeneric 10/2016
1	tempolIBA 10/2016
1	ResveratrolIBA 10/2016
1	SandIBA 12/2015
1	Cholinergic ReceptorsIBA 11/2014
1	Adrenergic Agents (Adrenergic Drugs)IBA 11/2014
1	Cholinergic Agents (Cholinergics)IBA 11/2014
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 11/2014
1	Infliximab (Remicade)FDA Link 01/2014
1	DNA (Deoxyribonucleic Acid)IBA 08/2013
1	A-Form DNA (A-DNA)IBA 08/2013
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 10/2012
1	Antiparasitic Agents (Antiparasitics)IBA 10/2012
1	cobaltiprotoporphyrinIBA 07/2012
1	MB Form Creatine KinaseIBA 01/2012

Therapy/Procedure

12	Therapeutics 01/2022 - 07/2009
1	Investigational Therapies (Experimental Therapy) 10/2016
1	Combination Drug Therapy (Combination Chemotherapy) 01/2016
1	Microspheres (Microsphere) 08/2013